Doctoral dissertations

Xu Yan
New insight into mechanisms of transcellular propagation of tau and α-synuclein in neurodegenerative diseases.
University of Helsinki, February 2017, Supervisor: Henri Huttunen

Tiina Etelälahti:
Voluntary alcohol drinking: Relation to corticosteroids and alcohol-mediated testosterone elevation.
University of Helsinki, January 2017, Supervisors: Kristian Donner and C.J. Peter Eriksson

Shrikanth Kulashekhar
The role of cortical oscillations in the estimation and maintenance of sensory and duration information in working memory.
University of Helsinki, January 2017, Superviros: Satu Palva and Matias Palva.

Vilma Aho
Kuolema kuittaa univelat? Effects of cumulative sleep loss on immune functions and lipid metabolism
University of Helsinki, November 2016, Supervisors: Tarja Stenberg and Henna-Kaisa Wigren

Silvia Bona
Investigating the functional roles of occipital face area and lateral occipital cortex with transcranial magnetic stimulation
University of Helsinki, September 2016, Supervisors: Juha Silvanto and Teija Kujala

Hanna Antila
Activation of the TrkB neurotrophin receptor by antidepressant drugs
University of Helsinki, September 2016, Supervisors: Eero Castren and Tomi Rantamäki

Ana Cathia Magalhaes
On the mechanisms of neural development in the ventral telencephalon
University of Helsinki, June 2016, Supervisor: Claudio Rivera

Jussi Alho
Speech motor system mediates phonetic categorization
Aalto University, June 2016, Supervisor Mikko Sams

Alexey Yukin
Animal models of early brain disorders: behavioural and electrophysiological approaches
University of Helsinki, May 2016, Supervisors: Kai Kaila and Juha Voipio

Johanna Mäkelä
Neuroprotective effects of PGC-1α activators in dopaminergic neurons
University of Helsinki, May 2016, Supervisor: Dan Lindholm

Stanislav Rozov
Circadian and histaminergic regulation of the sleep-wakefulness cycle
University of Helsinki, May 2016, Supervisor: Pertti Panula

Mateusz Dudek
Functional imaging of neural systems associated with alcohol reward and amphetamine toxicity
University of Helsinki, May 2016, Supervisor: Petri Hyytiä

Juho Kokkala
Particle and sigma-point methods for state and parameter estimation in nonlinear dynamic systems.
Aalto University, March 2016, Supervisor: Jouko Lampinen

Anne Mandel
Brain correlates of social cognition and interaction.
Aalto University, January 2016, Supervisor: Riitta Hari

Xiang Zhao
HMGB1 (Amphoterin) and AMIGO1 in brain development
University of Helsinki, January 2016, Supervisor: Heikki Rauvala

Enrico Glerean
Dynamic similarity of brain activity in humans: from single areas to functional networks.
Aalto University, December 2015, Supervisor: Mikko Sams

Dina Popova
Neurophysiological mechanisms of plasticity induced in adult brain.
University of Helsinki, December 2015, Supervisors: Tomi Taira, Eero Castren

Fariba Sharifian
Model-based exploration of interactions in the visual cortex
Aalto University, December 2015, Supervisor: Simo Vanni

Siina Pamilo
New approaches to statistical analysis of fMRI data
Aalto University, December 2015, Supervisor: Riitta Hari

Katja Airaksinen
Modifications of cortical activity by deep brain stimulation in advanced Parkinson's disease: an MEG study.
University of Helsinki, November 2015, Supervisors: Jyrki Mäkelä, Eero Pekkonen

Mordekhay Medvedovsky
Methodological and clinical aspects of ictal and interictal MEG.
University of Helsinki, October 2015, Supervisors: Jyrki Mäkelä, Ritva Paetau

Otto Manninen
Imaging studies in the mouse model of progressive myoclonus epilepsy of Unverricht-Lundborg type, EPM1
University of Helsinki, October 2015, Supervisor: Anna-Elina Lehesjoki, Outi Kopra

Natalia Luchkina
Developmentally regulated induction and expression mechanisms of long-term potentiation at hippocampal CA3-CA1 synapses
University of Helsinki, September 2015, Supervisor: Tomi Taira, Sari Lauri

Jussi Kupari
Studies on peripheral nervous system development and function in mice lacking the neurturin receptor GFRα2
University of Helsinki, August 2015, Supervisor: Matti Airaksinen

Anton Tokariev
Studying connectivity in the neonatal EEG.
University of Helsinki, August 2015, Supervisors: Sampsa Vanhatalo, Matias Palva

Julio Cesar Hernandez-Pavon
Transcranial magnetic stimulation and EEG in studies of brain function.
Aalto University, August 2015, Supervisor: Risto Ilmoniemi

Nora Bourbia
Central nucleus of the amygdala in descending control of pain-related behavior.
University of Helsinki, August 2015, Supervisor: Antti Pertovaara

Lotta Hirvenkari
Natural stimuli and experimental setups in the study of the neural basis of social interaction.
University of Helsinki / Aalto University, May 2015, Supervisor: Riitta Hari

Lauri Louhivuori
Calcium a key player in early neural development and migration: TRPCs and VGCCs.
University of Helsinki, May 2015, Supervisor: Karl Åkerman

Mikhail Kislin
Fine morphological alterations during brain injury and recovery analyzed with intravital microscopy.
University of Helsinki, May 2015, Supervisors: Leonard Khirug, Heikki Rauvala

Kai Kysenius
PCSK9 and berberine as modulators of lipoprotein receptors and neuronal cell death.
University of Helsinki, May 2015, Supervisor: Henri Huttunen

Juuso Juuri
Kainate-type glutamate receptors modulating network activity in developing hippocampus.
University of Helsinki, May 2015. Supervisors: Tomi Taira, Sari Lauri

Elyana Saad
Interaction between visual perception and mental representations of imagery and memory in the early visual areas. University of Helsinki, May 2015. Supervisors: Juha Silvanto, Teija Kujala

Jenni Vanhanen
Neuronal histamine and H3 receptor in alcohol-related behaviors - Focus on the interaction with the dopaminergic system
University of Helsinki, January 2015: Supervisor: Pertti Panula

Juha Lahnakoski
Brain mechanisms underlying perception of naturalistic social events
Aalto University, January 2015. Supervisor: Iiro Jääskeläinen, Lauri Nummenmaa

Komulainen, Emilia
JNK regulates dendrite and spine architecture in the central nervous system influencing spatial learning and motor tasks.
Åbo Akademi, January 2015, Supervisor: Eleanor Coffey

Olli Pietiläinen
Rare genomic deletions underlying schizophrenia and related neurodevelopmental disorders
University of Helsinki, December 2014: Supervisor: Aarno Palotie

Mikko Koskinen
F-actin dynamics turnover in dendritic spines
University of Helsinki, December 2014: Supervisor: Pirta Hotulainen

Robert Boldt
Functional and anatomical brain networks: Brain networks during naturalistic auditory stimuli, tactile stimuli and rest. Functional plasticity in early-blind subjects.
University of Helsinki, December 2014: Supervisor: Synnöve Carlson

Arto Lipponen
Hippocampal field potentials in animal models of Alzheimer's disease.
University of Eastern Finland, December 2014: Supervisor: Heikki Tanila

Justyna Zdrojewska
The interplay of JNK and SCG10 during cortical development and in excitotoxic responses in brain.
Åbo Akademi, October 2014, Supervisor: Eleanor Coffey

Enzo Scifo
Systematic Analysis of disease pathways in Congenital, Infantile and Juvenile Neuronal Ceroid Lipofuscinoses
University of Helsinki, September 2014, Supervisor: Marc Baumann, Maciej Lalowski

Alise Hyrskyluoto
Endoplasmic Reticulum Stress, Regulation of Autophagy and Ubiquitin-proteasome System in Cellular Models of Huntington’s Disease
University of Helsinki, September 2014, Supervisor: Dan Lindholm

Dmitry Molotkov
Role of Actin-mediated Motility of Peripheral Astrocytic Processes in Synaptic Function
University of Helsinki, June 2014, Supervisors: Leonard Khirug & Eero Castren

Mohamed Helmy
Mechanisms of birth asphyxia and a novel resuscitation strategy
University of Helsinki, April 2014, Supervisors: Kai Kaila & Juha Voipio

Henri Autio
The effects of anticholinesterases and β-amyloid pathology on neurotrophin signaling in the mouse brain

University of Helsinki, October 2013, Supervisor: Eero Castren

Johanna Huupponen
Synaptic mechanisms of Hebbian and homeostatic plasticity driven by intrinsic activity in the developing hippocampus
University of Helsinki, December 2013, Supervisors: Tomi Taira & Sari Lauri

Raili Koivuniemi
Regulation of neural progenitor cell proliferation and fate by proteolytic pathways and inflammatory signals in the brain
University of Helsinki, September 2013, Supervisor: Dan Lindholm

Lauri Kovanen
Computational analysis of large and time-dependent social networks
Aalto University, May 2013, Supervisor: Jari Saramäki

Lauri Nurminen
Spatial context in the early visual system
University of Helsinki / Aalto University, August 2013, Supervisor: Simo Vanni

Madhusmita Priyadarshini
Neurobiology of Parkinson s Disease Gene Pink1 in Danio rerio (Zebrafish)
University of Helsinki, December 2013, Supervisor: Pertti Panula

Martin Pushkarjov
KCC2 as a multifunctional protein in brain development and disease
University of Helsinki, November 2013, Supervisor: Kai Kaila

Iikka Salmela
Biophysics of night vision: Cockroach (Periplaneta americana) photoreceptors as a model system
University of Oulu, November 2013, Supervisor: Matti Weckström

Saara Tegelberg
Early neuropathological changes in the mouse model for progressive myoclonus epilepsy of Unverricht-Lundborg type, EPM1
University of Helsinki, November 2013, Supervisor: Anna-Elina Lehesjoki

Elena Vashchinkina
Tonic GABAergic inhibition as a new way to regulate mesolimbic dopamine system
University of Helsinki, December 2013, Supervisor: Esa Korpi

Faraz Ahmad
Post-translational regulation of KCC2 in the rat hippocampus
University of Helsinki, June 2012. Supervisors: Kai Kaila & Peter Blaesse 

Jaakko Kauramäki
Measures and Models of Top-Down Influences in the Human Auditory Cortex
Aalto University, May 2012, Supervisors: Mikko Sams & Iiro Jääskeläinen

Hannu Laaksonen
Cortical rhythms as markers of neural processing
Aalto University, October 2012, Supervisor: Riitta Salmelin

Satu Lamminmäki
Auditory cortical processing: Binaural interaction in healthy and ROBO1-deficient subjects
Aalto University, November 2012, Supervisor: Riitta Hari

Katri Niemi
Serum amyloid A (SAA) - Proinflammatory functions and their regulation by serum lipoproteins
University of Helsinki, November 2012, Supervisor: Marc Baumann

Xavier Ekolle Ndode-Ekane
Mechanisms of Tissue Remodeling in Acquired Epilepsy
University of Eastern Finland, December 2012, Supervisor: Asla Pitkänen

Pavan Ramkumar
Advances in Modeling and Characterization of Human Neuromagnetic Oscillations

Aalto University, May 2012, Supervisor: Riitta Hari

Kirsi-Marja Rytkönen
The puzzle of decreased homeostatic slow wave sleep in aging
University of Helsinki, November 2012, Supervisor: Tarja Stenberg

Janneke Zant
What keeps us awake? The role of the ascending arousal systems in the regulation of sleep and wakefulness mediated by the basal forebrain.
University of Helsinki, November 2012, Supervisor: Tarja Stenberg

Arto Piironen
Novel experimental methods for insect neurophysiology
University of Oulu, December 2011, Supervisor: Matti Weckström

Hultén, Annika
Neural correlates of language learning in adults
Åbo Akademi University & Aalto University, April 2011, Supervisor: Riitta Salmelin

Stanislav Khirug
Functional expression and subcellular localization of the Cl- cotransporters KCC2 and NKCC1 in rodent hippocampal and neocortical neurons

University of Helsinki, September 2011, Supervisor: Kai Kaila

Elli Leppä
A new method for modulating the activity of parvalbumin-positive neurons and cerebellar Purkinje cells in vivo

University of Helsinki, September 2011, Supervisor: Esa Korpi

Mikael Segerstråle
Tonically Active Kainate Receptors (tKARs) - A Novel Mechanism Regulating Neuronal Function in the Brain

University of Helsinki, October 2011, Supervisor: Tomi Taira

Kaia Achim
Regulation of gabaergic neuron identity and diversity in the developing midbrain.

University of Helsinki, September 2010, Supervisor: Juha Partanen

Natalia Gass
Molecular pathways of disturbed sleep and depression: Studies on adenosine and gene expression patterns
University of Helsinki, December 2010, Supervisor: Tarja Stenberg

Linda Henriksson
Imaging studies on the functional organization and plasticity of human visual cortex
.

Aalto University, February 2010, Supervisor: Simo Vanni

Miiamaaria Kujala
Social perception and cognition: processing of gestures, postures and facial
expressions in the human brain
.

Aalto University, June 2010, Supervisor: Riitta Hari

Mia Liljeström
Imaging language function with MEG and fMRI.

Aalto University, May 2010, Supervisor: Riitta Salmelin

Sanna Malinen
Data-analysis perspectives on naturalistic stimulation in functional
magnetic resonance imaging
.

Aalto University, June 2010, Supervisor: Riitta Hari

Ville Renvall
Studying functional magnetic resonance imaging with articifial imaging objects.

Aalto University, March 2010, Supervisor: Riitta Hari

Linda Stenbacka
Functional imaging of peripheral vision and dorsal visual stream in human cerebral cortex
Aalto University, May 2010, Supervisor: Simo Vanni

Pavel Uvarov
Neuronal K-Cl Cotransporter - Transcriptional Mechanisms of KCC2 Gene Regulation
University of Helsinki, June 2010, Supervisor: Matti Airaksinen

Johanna Vartiainen
Multimodal imaging of language perception 

Aalto University, June 2010, Supervisor: Riitta Salmelin

Tero Viitanen
GABAa Receptor Mediated Signalling in the Brain: Inhibition, Shunting and Excitation
University of Helsinki, June 2010, Supervisors: Juha Voipio & Kai Kaila

Suvi Asikainen
Small RNA-mediated gene regulation in Caenorhabditis elegans
.

University of Kuopio, November 2009, Supervisor: Garry Wong

Mirka Jokela-Määttä
Molecular tuning of rhodopsins for high visual sensitivity in different light environments -
Variation in absorbance spectrum and opsin sequence within and between species
.

University of Helsinki, October 2009, Supervisor: Kristian Donner

Tommi Möykkynen
Trafficking and ethanol-induced inhibition of AMPA receptors.
University of Helsinki, June 2009, Supervisor: Esa Korpi

Lauri Parkkonen
Expanding the applicability of magnetoencephalography
.

University of Helsinki, June 2009, Supervisor: Riitta Hari

Ville Sallinen
Zebrafish as a model of Parkinson’s disease.
University of Helsinki, June 2009, Supervisor: Pertti Panula

Nuutti Vartiainen
Brain imaging of chronic pain
.

Helsinki University of Technology, November 2009, Supervisor: Riitta Hari

Henna-Kaisa Wigren
Cellular mechanisms of sleep homeostasis : Studies on brain energy metabolism and aging
.

University of Helsinki, February 2009, Supervisor: Tarja Stenberg

Liying Yu
Death pathways activated in the neurotrophic factor-deprived neurons
.

University of Helsinki, February 2009, Supervisor: Urmas Arumäe

Jan Kujala
Study of cortical rhythmic activity and connectivity with magnetoencephalography.
Helsinki University of Technology, April 2008, Supervisor: Riitta Salmelin

Hong Li
Structural and functional roles of KCC2 in the developing cortex
.

University of Helsinki, February 2008, Supervisors: Claudio Rivera, Kai Kaila

Anastasia Ludwig
Mechanisms of KCC2 upregulation during development
University of Helsinki, November 2008, Supervisors: Claudio Rivera, Mart Saarma

Francisco López Picón
Neurofilament proteins in the postnatal rat hippocampus. Developmental expression and changes in experimental epilepsy

University of Turku, June 2008, Supervisor: Irma Holopainen

Mikhail Paveliev
Co-signaling by neurotrophic factors and the extracellular matrix for axonal growth and neuronal survival

University of Helsinki, December 2008, Supervisor: Mart Saarma

Eva Ruusuvuori
Ion-regulatory proteins in neuronal development and communication
University of Helsinki, November 2008, Supervisors: Kai Kaila, Juha Voipio

Topi Tanskanen
Dynamics of contour, object and face processing in the human visual cortex
University of Helsinki / Helsinki University of Technology, May 2008, Supervisor: Riitta Hari

Virve Vuontela
Developmental, functional brain imaging and electrophysiological evidence of visual and auditory working memory
.

University of Helsinki, January 2008, Supervisor: Synnöve Carlson

Anniina Alakuijala
Expression of functional GABAc reseptors in the brain
.

University of Helsinki, October 2007, Supervisor: Michael Pasternack

Gina Caetano
Brain mechanisms of audiotactile and audiomotor interactions
.

Helsinki University of Technology, December 2007, Supervisor: Riitta Hari

Anni Hienola
N-syndecan and HB-GAM in neural migration and differentiation - Modulation of growth factor activity in brain
.

University of Helsinki, February 2007, Supervisor: Heikki Rauvala

Yevhen Hlushchuk
Tactile processing in human somatosensory and auditory cortices
.

University of Helsinki and Helsinki University of Technology, January 2007, Supervisor: Riitta Hari

Vesa Hongisto
The role of GSK-3 and JNK in neuronal apoptosis
.

Åbo Akademi University, January 2007, Supervisor: Eleanor Coffey

Johan Pahlberg
Spectral Tuning and Adaptation to Different Light Environments of Mysid Visual Pigments
.

University of Helsinki, October 2007, Supervisor: Kristian Donner

Tiina Parviainen
Cortical Correlates of Language Perception: Neuromagnetic Studies in Adults and Children

University of Jyväskylä and Helsinki University of Technology, October 2007, Supervisor: Riitta Salmelin

Mika Seppä
Quality improvements for multi-modal neuroimaging
.

Helsinki University of Technology, September 2007, Supervisor: Riitta Hari

Helena Ojanpää
Visual search and eye movements: Studies of perceptual span
.

University of Helsinki, November 2006, Supervisors: Veijo Virsu and Risto Näsänen

Ivan Pavlov
Heparin-binding growth-associated molecule (HB-GAM) in activity-dependent neuronal plasticity in hippocampus.
University of Helsinki, March 2006, Supervisors: Tomi Taira and Sari Lauri

Tomi Rantamäki
Brain TrkB neurotrophin receptor as a target for antidepressant treatments
.

University of Helsinki, October 2006, Supervisor: Eero Castren

Sanna Partanen
Cathepsin D Deficiency - Molecular and Cellular Mechanisms of Neurodegeneration
.

University of Helsinki, November 2006, Supervisors: Marc Baumann and Jaana Vesterinen

Vootele Võikar
Evaluation of methods and applications for behavioural profiling of transgenic mice
.

University of Helsinki, August 2006, Supervisor: Heikki Rauvala

Irina Anurova
Processing of spatial and nonspatial auditory information in the human brain
.

University of Helsinki, June 2005, Supervisor: Synnöve Carlson

Juha Järveläinen
Reactivity of the human primary motor cortex during observation of action.
Helsinki University of Technology, March 2005, Supervisor: Riitta Hari

Matias Palva
Interactions among neuronal oscillations in the developing and adult brain.

University of Helsinki, November 2005, Supervisors: Kai Kaila and Juha Voipio
Novartis-Exelon Thesis Prize 2005; University of Helsinki Thesis Prize 2005

Marjatta Pohja
Motor cortex-muscle oscillatory communication in health and disease
University of Helsinki and Helsinki University of Technology, October 2005
Supervisor: Riitta Hari

Tuukka Raij
Processing of acute pain in the human brain - magnetoencephalographic and functional magnetic resonance imaging studies
Helsinki University of Technology, May 2005, Supervisors: Riitta Hari and Nina Forss

Minna-Liisa Änkö
Neuropeptide FF and related RF amide peptides in G protein coupled receptor -mediated signal transduction

Åbo Akademi, December 2005, Supervisor: Pertti Panula

Jan Kaslin
The aminergic and cholinergic neurotransmitter systems in the zebrafish brain
Åbo Akademi, November 2004, Supervisor: Pertti Panula

Samuli Kemppainen
Chemoarchitectonic and connectional characteristics of the rat amygdaloid complex and changes of amygdalo-hippocampal connectivity in temporal lobe epilepsy
University of Kuopio, June 2004, Supervisor: Asla Pitkänen

Sari Lähteinen
Brain-derived neurotrophic factor in the development of epilepsy

University of Kuopio, June 2004, Supervisors: Eero Castren, Asla Pitkänen

Riikka Möttönen
Cortical mechanisms of seeing and hearing speech

Helsinki University of Technology, December 2004, Supervisor: Mikko Sams

Johanna Nystedt
The transcriptional regulation of the neuropeptide FF gene
Åbo Akademi, April 2004, Supervisor: Pertti Panula

Mikko Vähäsöyrinki
Voltage-gated K+ channels in Drosophila photoreceptors. Biophysical study of neural coding.
University of Oulu, December 2004, Supervisor: Matti Weckström

Annakaisa Haapasalo
Localization and function of trkB neurotrophin receptor isoforms in neuronal cells

University of Kuopio, May 2003, Supervisors: Eero Castren, Garry Wong

Nina Peitsaro
Molecular and functional characterization of vertebrate brain histamine and histamine receptors
Åbo Akademi, June 2003, Supervisor: Pertti Panula

Antti Tarkiainen
Cortical Dynamics of Visual Feature and Object Processing in the Human Occipitotemporal Cortex: MEG Source Analysis and Evaluation of Conductivity Models
Helsinki University of Technology, March 2003, Supervisor: Riitta Salmelin

Marylka Uusisaari
GABAergic mechanisms of excitation and hypersynchrony in adult rat hippocampus
University of Helsinki, March 2003, Supervisors: Kai Kaila, Juha Voipio

Jaana Suopanki
Studies on palmitoyl protein thioesterase1
University of Helsinki, May 2002, Supervisor: Marc Baumann

Marja Laasonen
Temporal acuity in developmental dyslexia across the life span: Tactile, auditory, visual and crossmodal estimations
University of Helsinki, November 2002, Supervisor: Veijo Virsu

Johanna Silvennoinen
A Study of NMR Relaxation in Blood: Mechanistic Considerations and Implications for Quantitative Functional MRI
University of Kuopio, November 2002, Supervisor: Risto Kauppinen

Kimmo Uutela
Estimating Neural Currents From Neuromagnetic Measurements
Helsinki University of Technology, December 2001, Supervisors: Matti Hämäläinen, Riitta Hari

Karri Lämsä
GABAA Receptor-Mediated Excitation in the Hippocampus of Adult and Newborn Rats
University of Helsinki, October 2004, Supervisors: Tomi Taira, Kai Kaila

Katri Wegelius
Distribution and Function of GABA Receptor rho Subunits in the Rat Nervous System

University of Helsinki, June 2000, Supervisors: Michael Pasternack, Kai Kaila

Nanna Fyhrquist
Spectral and Thermal Properties of Amphibian Visual Pigments Related to Molecular Structure
University of Helsinki December 1999, Supervisor: Kristian Donner

Päivi Helenius
Neuromagnetic and Psychoacoustical Correlates of Impaired Reading and Abnormal Sound Sequence Processing in Developmental Dyslexia
Helsinki University of Technology June 1999, Supervisors: Riitta Hari, Riitta Salmelin

Sirpa Nummela
Scaling and Modelling of the Mammalian Middle Ear
University of Helsinki May 1999, Supervisor: Tom Reuter

Simo Vanni
Visual Prosessing in the Human Cerebral Cortex: Neuromagnetic Studies
Helsinki University of Technology September 1998, Supervisor: Riitta Hari